Characterization And Antifungal Activity Evaluation Of Tamanu Seed Oil Based Liquid Soap Towards Candida Albicans
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Abstract
Candida albicans fungal infection towards skin could be prevented by using the soap with antifungal activity. Material used for the soap making was tamanu oil which was potential as antifungal soap. This study aims to find out the best characteristic liquid soap and to evaluate its antifungal activity towards Candida albicans. The methods used in this research were maseration and followed by soap making using semi-boiled method. Tamanu seed oil based liquid soap was formulated with variety concentrations of bacang leave extract as an antifungal agent and nutmeg leave extract as foaming agent. Each soap were characterized following the SNI 4085:2017 standard. The liquid soap formula with the best characteristic was determined and its antifungal activity towards Candida albicans was tested using disk diffusion method. The result shows that the best soap formula is the tamanu oil based liquid soap with the addition of 0.9% bacang leave extract and 0,9% nutmeg leave extract (SFM5P5). The best formula had 9.25 pH value; 18,3017% total active agent, 3,3840% free fatty acid; 1,0235 g/mL density and 94,1176% foam stability. In conclusion, liquid soap has strong activity to inhibit the fungal growth of Candida albicans with 18.18 mm of inhibition zone diameter.
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References
Adventi, F. (2018) Pengaruh Suhu Reaksi, Kecepatan Pengadukan, dan Waktu Reaksi pada Pembuatan Sabun Padat dari Minyak Kelapa. Skripsi. Medan: Universitas Sumatera Utara.
Anggraeni, Y., Nisa, F., & Betha, O. (2020). Physical Characteristics and Antibacterial Activity of Patchouli Oil (Pogostemon cablin Benth.) Liquid Soaps Based on Sodium Lauryl Ether Sulphate Surfactant. Jurnal Kefarmasian Indonesia, 10(1): 1-10.
Arifin, Z. (2018). Aktivitas antijamur ekstrak etil asetat daun mangga bacang (Mangifera foetida L.) terhadap Candida albicans secara in vitro. Jurnal Mahasiswa PSPD FK Universitas Tanjungpura, 4(3).
Artanti, A., Rahmawati, K., Rakhmawati, R., & Prihapsara, F. (2020). Uji Aktivitas Antibakteri dan Antijamur dari Kombinasi Minyak Nyamplung (Callophyllum Inophyllum L.) dengan Virgin Coconut Oil dan Pengembangannya sebagai Face Oil. Jurnal Farmasi Indonesia, 17(2): 17-29.
Ayu, D., Ali, A., & Sulaiman, R. (2010). Evaluasi Mutu Sabun Padat dari Minyak Goreng Bekas Makanan Jajanan di Kecamatan Tampan Kota Pekanbaru dengan Penambahan Natrium Hidroksida dan Lama Waktu Penyabunan. Prosiding, Pekanbaru: Konferensi dan Seminar Nasional XX Badan Kerjasama Pusat Studi Lingkungan - Seminar Nasional Lingkungan.
Chasani, M., Widyaningsih, S., & Mubarok, A. (2015). Sintesis dan Karakterisasi Sabun Natrium dari Minyak Biji Nyamplung (Calophyllum inophyllum L.) Serta Uji Aktivitas Antibakteri terhadap Staphilococus aureus. Jurnal Molekul, 10(1): 66-73.
Dinata, A., Rosyandi, A., Hamid, S., & Zainul, R., 2018, A Rieview Chemical Vapor Deposition: Proses and Aplication. Retrieved Juli 2, 2020, https://osf.io/preprints/inarxiv/yfeau/. was accesed on January 13, 2021.
Fitmawati, F., Fauziah, R., Hayati, I., Sofiyanti, N., Inoue, E., & Matra, D. (2017). Phylogenetic analysis of Mangifera from central region of Sumatra using trnL-F intergenic spacer. Biodiversitas Journal of Biological Diversity, 18(3): 1035-1040.
Fitria, L., Shahib, M., & Sastramihardja, H. (2020). Perbedaan Penurunan Jumlah Koloni Candida albicans antara Pemberian Cebokan Rebusan Biji Manjakani dan Daun Sirih Merah pada Wanita Usia Subur (WUS) yang Mengalami Keputihan. Jurnal Medikes, 7(1): 185-196.
Minarno, B., 2016, Analisis Kandungan Saponin pada Daun dan Tangkai Daun Carica pubescens Lenne & K.Koch. El-Hayah, 5(4): 394-401.
Musta, R., Haetami, A., & Salmawati, M. (2017). Biodiesel of The Transesterification Product of Callophyllum inophyllum Seed Oil from Kendari Using Methanol Solution. Indonesian Journal of Chemical Reasearch, 4(2): 394-401.
Nurhadi, S. (2012). Pembuatan Sabun Mandi Gel Alami dengan Bahan Aktif Mikroalga (Chlorrela pyrenoidosa Byerinck) dan Minyak Atsiri (Lavandula lativolia Chaix). Skripsi. Malang: Universitas Ma Chung.
Oroh, S., Kandou, F., Pelealu, J., & Pandiangan, D. (2015). Uji daya hambat ekstrak metanol Selaginella delicatula dan Diplazium dilatatum terhadap bakteri Staphylococcus aureus dan Escherichia coli. Jurnal Ilmiah Sains, 15(1): 52-58.
Pohan, A., Purwaningsih, E., & Dwijayanti, A. (2013). Efek Kelasi Ekstrak Etanol Daun Mangifera foetida pada Feritin Serum Penderita Talesmia di RS Cipto Mangunkusumo. Journal of The Indonesian Medical Association, 1(1): 45-52.
Puspa, O., Syahbanu, I., & Wibowo, M. (2017). Uji Fitokimia dan Toksisitas Minyak Atsiri Daun Pala (Myristica fragnans Houtt) dari Pulau Lemukutan. Jurnal Kimia Khatulisiwa, 6(2): 1-6.
Seru, R., Suling, P., & Pandeleke, H. (2013). Profil Kandidiasi Kutis Poliklinik Kulit dan Kelamin RSUP Prof. Dr. R.D Kandou Manado Periode 2009-2011. Jurnal e-Biomedik, 1(1): 561-565.
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